Dream Team brings you all the latest injury, suspension and selection updates ahead of Game Week 28 in one easily digestible dose.
League leaders Arsenal will be without first-choice centre-back William Saliba (£3.2m) for Leeds’ visit to the Emirates.
The Frenchman has been ruled out of the game with an ongoing back problem.
Meanwhile, Javi Gracia has been majorly inconvenienced by the international break as Tyler Adams (£1.2m), Max Wober (£2.2m) and Wilfried Gnonto (£2.4m) returned from their respective nations with injuries – the USA international may not return before end of the campaign.
Luis Diaz (£5.2m) is close to return to full training but this weekend’s clash with Man City comes too soon for the Colombian winger.
Darwin Nunez (£5.2m) is “in contention” to play at the Etihad despite missing training earlier in the week.
A question mark remains over Erling Haaland’s (£9.3m) availability following Pep Guardiola’s non-committal comments to reporters.
“Yesterday I spoke with him, he feels good, but we will see,” the decorated tactician said of his side’s top scorer.
Phil Foden (£5.1m) will be out for at least a fortnight having had his appendix removed.
Marcus Rashford (£6.5m) missed England’s Euro qualifiers but Erik ten Hag is optimistic of the 25-year-old’s chances of making Man United’s trip to Newcastle.
“I think we have one more day so I have good hope he’s available,” the Dutchman told journalists at his Friday press conference.
Nick Pope (£4m) has all but fully recovered from his thigh injury and is likely to start for the Magpies.
Reece James (£5.7m) and Kai Havertz (£4m) have returned to training after withdrawing from international duty and should be available with Chelsea set to host Aston Villa on Saturday afternoon.
N’Golo Kante (£2.8m) played a friendly during the break but it’s not known to what extent he will feature this weekend.
Fraser Forster’s (£3m) spell between the sticks for Spurs may be at an end as Hugo Lloris (£3.4m) has returned to full training.
David Moyes has doubts over some key players ahead of West Ham’s must-win game against Southampton this weekend.
Nayef Aguerd (£3m) has a “grumbly hip” while Gianluca Scamacca (£2.6m) is nursing a “sore knee” – a late decision will be made on both.
Saints have issues too with Armel Bella-Kotchap (£1.6m) an absentee and Juan Larios ruled out for the remainder of the season.
Che Adams (£3.3m) and Mohammed Salisu (£1.3m) will also need to be assessed before Sunday’s trip to east London.
Injuries: Mohamed Elneny,, Eddie Nketiah, William Saliba, Kieran Tierney (doubt), Thomas Partey (doubt), Takehiro Tomiyasu
Injuries: Matty Cash, Philippe Coutinho, Boubacar Kamara (doubt)
Injuries: Junior Stanislas (doubt)
Injuries: Kristoffer Ajer, Keane Lewis-Potter, Vitaly Janelt
Suspensions: Shandon Baptisite
Injuries: Jakub Moder, Adam Lallana, Tariq Lamptey (doubt), Jeremy Sarmiento
Injuries: Edouard Mendy (doubt), Armando Broja, Cesar Azpilicueta, Thiago Silva, Reece James (doubt), Raheem Sterling, Wesley Fofana
Injuries: Nathan Ferguson, Joachim Andersen (doubt), Chris Richards
Injuries: Andros Townsend, Dominic Calvert-Lewin
Injuries: Neeskens Kebano, Layvin Kurzawa, Shane Duffy (doubt)
Suspensions: Willian, Aleksandar Mitrovic
Injuries: Stuart Dallas, Adam Forshaw, Max Wober, Wilfried Gnonto, Tyler Adams
Injuries: Ryan Bertrand, James Justin, Youri Tielemans, Victor Kristiansen (doubt), Jonny Evans (doubt), Harry Souttar (doubt), Dennis Praet (doubt)
Injuries: Luis Diaz, Thiago Alcantara, Naby Keita, Stefan Bajcetic
Injuries: Phil Foden, Erling Haaland (doubt)
Injuries: Donny van de Beek, Christian Eriksen, Anthony Martial (doubt), Marcus Rashford (doubt), Tom Heaton, Alejandro Garnacho, Raphael Varane (doubt)
Injuries: Emil Krath, Miguel Almiron, Nick Pope (doubt), Sven Botman (doubt), Anthony Gordon (doubt)
Injuries: Omar Richards, Dean Henderson, Taiwo Awoniyi doubt), Cheikhou Kouyate (doubt), Giulian Biancone, Willy Boly, Scott McKenna, Scarpa, Chris Wood, Wayne Hennessey, Serge Aurier, Andre Ayew, Brennan Johnson (doubt), Ryan Yates (doubt)
Injuries: Tino Livramento, Juan Larios, Armel Bella-Kotchap, Che Adams (doubt), Mohammed Salisu (doubt)
Injuries: Yves Bissouma, Ryan Sessegnon, Rodrigo Bentacur, Richarlison, Ben Davies, Emerson Royal
Injuries: Lukasz Fabianski (doubt), Gianluca Scamacca (doubt), Nayef Aguerd (doubt), Michail Antonio (doubt)
Injuries: Chiquinho, Sasa Kalajdzic, Hwang Hee-chan