In a game where Luis Enrique’s side were frustrated by the tactical masterclass of the Old Lady, one moment in the first half resulted in one of the major talking points.
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With the ball looping up by the halfway, Messi went up for a header against Miralem Pjanic, but the midfielder stood his ground, with the 29-year-old flying over his shoulder.
He couldn’t get his hands up to stop his fall and face-planted the floor, leaving him with a cut under his eye.
His team-mate Neymar was left outraged, and charged at the Bosnian star where he clattered him over, resulting in a yellow card.
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Fortunately he was able to finish off the match, but failed to provide any spark for the Catalan club, before he was the subject of a battle between Giorgio Chiellini and Leonardo Bonucci who were vying for his shirt.
Social media went crazy after they witnessed the incident, with users creating meme after meme to perfect their photoshop skills.